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Gatsbys Corruptive Nature Essay Example For Students

Gatsbys Corruptive Nature Essay The Great Gatsby , composed by F. Scott Fitzgerald is a depiction of the shrinking of the American Dream....

Monday, September 30, 2019

Curley’s Wife Essay

Curley’s wife presented in a complicated way.. She is ambiguous in some sense. Dangerous: ‘both men glanced up for the rectangle of sunshine in the doorway was cut off. ’ ‘She had full rouged lips and wide-spaced eyes, heavily made up. ’ Red, foreshadowing danger. Vulnerable: ‘heavily made up. ’ Insecure. Hiding domestic violence. Mysterious. Outlet for feelings, only thing she has control over. Wants attention because she is neglected by Curley. ‘I don’t like Curley. He ain’t a nice fella. ’ She is a possession to Curley. She puts her hands behind her back leaned against the door frame so that her body was thrown forwards. ’ She is acting provocatively towards George and Lennie because she thinks that she can het their attention that she is lacking from her marriage. She closes off after she gets some attention from people especially Lennie because this is not what she wanted. She ‘looks at her fingernails’ which shows that she is not interested. She is commented in a derogatory way by the men. Steinbeck wants to teach people that we shouldn’t judge women. They think that she is immature and irresponsible. She is presented as spiteful and ungrateful in the middle of the novella by the way she treated other minor characters such as the black guy. ‘A bunch of bindlestiffs-a nigger an’ a dum-dum and lousy ol’ sheep. She is annoyed at how she is being treated by the other minor characters which lead her to this outbreak. She is worked up because she discriminates crooks by what she immediately sees. She repeats ‘and’ and this fractures her sentences. Curley’s neglected lead to her ability to act rational being affected. Exasperated and anguished by her own self because she likes talking to people. Women were treated worse than lowly ranch workers. Desperate and lonely way. Also relies on the American dream because she goes on multiple times about her dream to be a singer. She likes to be in the spotlight. Tumbled suggests that she is overwhelmed at the attention she is receiving from Lennie. Flowing out, hurried for her story to be heard. Afraid of Lennie neglecting her like Curley did. Curley’s wife is demanding and childish. She has restrictions from her husband. Acting like a child and questioning why. Confiding in Lennie because he has a low IQ level which means that he cannot tell everyone her secrets, hopes and dreams. When she dies she is presented in an innocent way. Her hair looks like a halo around her head. And she looks like an angel. This could suggest that people were recognised as important after they have died not when they are alive. Vulnerable because she is stripped of her make up. She has finally found peace and her pain was gone from her face. Makes us feel guilty about our assumptions on her. She questions people to start off a conversation; it is also a way to show that she wants answers. She is also insecure about who she can trust so she questions them to see if they are telling the truth. However, she will get defensive in the middle of the conversation when they have lied to her. Therefore, she uses sentences that do not make sense and exclamations. Juxtapositions in a paragraph could represent Curley’s wife’s ambiguous nature and her complex characteristics. Of Mice and Men is not kind in its portrayal of women. In fact, women are treated with contempt throughout the course of the book. Steinbeck generally depicts women as troublemakers who bring ruin on men and drive them mad. Curley’s wife, who walks the ranch as a temptress, seems to be a prime example of this destructive tendency—Curley’s already bad temper has only worsened since their wedding. Aside from wearisome wives, Of Mice and Men offers limited, rather misogynistic, descriptions of women who are either dead maternal figures or prostitutes. Despite Steinbeck’s rendering, Curley’s wife emerges as a relatively complex and interesting character. Although her purpose is rather simple in the book’s opening pages—she is the â€Å"tramp,† â€Å"tart,† and â€Å"bitch† that threatens to destroy male happiness and longevity—her appearances later in the novella become more complex. When she confronts Lennie, Candy, and Crooks in the stable, she admits to feeling a kind of shameless dissatisfaction with her life. Her vulnerability at this moment and later—when she admits to Lennie her dream of becoming a movie star—makes her utterly human and much more interesting than the stereotypical vixen in fancy red shoes. However, it also reinforces the novella’s grim worldview. In her moment of greatest vulnerability, Curley’s wife seeks out even greater weaknesses in others, preying upon Lennie’s mental handicap, Candy’s debilitating age, and the color of Crooks’s skin in order to steel herself against harm. Women had a profound sense of loneliness and they desire a friend or a companion. However, women like Curley’s wife will settle for an attentive ear from a stranger. Women were often unhappily married to help escape from the great depression in the USA. They were rendered helpless by their isolation and even at their weakest will seek to destroy those who were weaker. Oppression does not come from those who are strong or powerful but those who are also suffering. Strength is born from those who are weak and at their weakest. The American dream is impossible especially at the time of when of mice and men were set because this was the time of the great depression and the dust bowl where farmers were out of work and suffering. Therefore, Curley’s wife abandons her American dream and marries Curley for financial security. Women are not referred to by their names but by a pronoun. It shows that they are seen as mere possessions and not even real human beings. They are insignificant and inferior to others therefore they have no name. Curley’s wife is not given a name to represent the status of women in the 1930s. They were ranked as low as Black people such as crooks who is also not given a name. Alternative: Portrayal of women in of mice and men is unflattering and limited from the point of view of men. Women don’t have a place in the author’s vision of the world which was surrounded by bonds of men. Women are unimportant, thus they are portrayed in a negative light. Steinbeck: He was a feminist who helped raise the profile of women and their role in the 1930s. He also disagreed with the way women were treated because in the end he reveals the true nature of her and how she was not a bad person all along. He has also made Curley’s wife a complex character to teach readers of the 1930s that women also had feelings and were also as complex as the men. It also makes her not seem like a one dimensional character. The book only assigns women with two lowly roles of housewives or prostitutes. Female sexuality is a trap to ensnare men and ruin their lives. Temptation to men that will lead them to their fall from perfection. For example, George and Lennie who had their lives ruined by Curley’s wife. All characters are nearly all disempowered by Curley’s wife who discriminates the men by their race, intelligence and age. When Curley’s wife speaks to Lennie, the reader is afraid for Lennie because they can sense something bad will happen. Curley’s wife is depicted in a different way when she is speaking to Lennie because before she was easily dismissed as a flirt with a temper and a manipulator. However, in the final moments before her death, Steinbeck presents his sole female character sympathetically. Her loneliness becomes the focus of this scene, as she admits that she too has an idea of paradise that circumstances have denied her. Curley’s wife seems to sense, like Crooks (who notes earlier that Lennie is a good man to talk to), that because Lennie doesn’t understand things, a person can say almost anything to him. She confesses her unhappiness in her marriage, her lonely life, and her broken dreams in â€Å"a passion of communication. † Unfortunately, she fails to see the danger in Lennie, and her attempt to console him for the loss of his puppy by letting him stroke her hair leads to her tragic death. One might take issue with Steinbeck’s description of her corpse, for only in her death does he grant her any semblance of virtue. Once she lies lifeless on the hay, Steinbeck writes that all the marks of an unhappy life have disappeared from her face, leaving her looking â€Å"pretty and simple . . . sweet and young. † The story has spent considerable time maligning women, and much has been made of their troublesome and seductive natures. It is disturbing, then, that Steinbeck seems to subtly imply that the only way for a woman to overcome that nature and restore her lost innocence is through death. Because Curley’s wife cannot bare her lonely soul to the men around her, the men persist in believing she is merely a â€Å"lousy tart. † This is due to misinterpretations by other characters. Her unattainable dreams make he seem human and the writer reiterates this through the innocence of her face in the time of her death. In sharing his vision of what it means to be human, Steinbeck touches on several themes: the nature of dreams, the nature of loneliness, man’s propensity for cruelty, powerlessness and economic injustices, and the uncertainty of the future.

Sunday, September 29, 2019

Girl Before the Mirror Essay

The painting by Pablo Picasso â€Å"Girl Before the Mirror† was the painting that caught my attention because at first glance I notice a woman adjusting the mirror as she is looking at her reflection; this is something I do every day. I gazed longer at the painting and the woman’s appearance seems to be younger in the mirror, perhaps she is reflecting on her past (youth). The dialogue taking place in this story is with herself as she is reflecting on the many years that have passed and how her appearance has changed. Her pregnancy has captured her attention to the changes in her life. The painting reflects the past, present, and future. The different colors, lines, and shapes tell a story about her development. The colors in the mirror are deep dark in color representing a faint memory of what once was. Looking at herself in the mirror gives her a sense of relief yet pain. She can still see a little of her youth in the mirror, which easies some of her distress as she is aging knowing one day that the memories of her youth will soon fade. The long strokes of lines and curves in the mirror by her face and around her head display a covering a sense of innocence; before she has known a man intimately. The lines in the lower area of her body in the mirror shows it is still in development as the lines are arched up and not down in a drooping manner as with age. Her body has not set firmly in position so it appears altered in the mirror just like a teenager starting puberty; one breast grows larger than the other. In her conversation with herself she knows her innocence has vanished, and a development is changing her life once again; the baby growing within her. The circles remind me of life. There is a beginning and an ending. The circles in this painting are in locations of the body that develop at a much faster pace than the rest of the body. The breast is developing in the mirror as the breast of the women looking at herself has full bulging breast because of her pregnancy. The circle in the stomach area in the mirror is low; the uterus, and it is still n the development stage. The circle in the stomach area of the women looking at herself in the mirror is fully developed. The black thick circle is completed meaning the uterus is fully developed and the green color almost filling the inside of the thick black circle is the womb. It is almost time to bring forth the baby into the world and life begins for the baby and the women looking at herself in the mirror. The circle on the elbow symbolizes the joints of the bones and is completely developed and aging. In pregnancy the baby will draw the calcium from the mother’s bones making the joints age and hurt. Her circle eyes in the mirror not fully develop like a baby’s ultrasound picture shows her childlike innocence. When a child looks at you unsure of something, his or her eyes become round in curiosity. The women looking at herself is thinking â€Å"where is my youth. I do not remember it fading away and I am starting a new chapter in my life and as I reflect on my new life with child I have to cope with my youth fading away. Thinking to herself further â€Å"will I remember my past,† as she looks at herself in the mirror; seeing a dim fraction of her youth. I believe this piece of art symbolize â€Å"reflection. † The mirror is the object of focus; at some point in life one looks back at the past whether it is in thought, pictures, or video. The days go by so fast and in the everyday activity of life that time becomes precious as it is very limited. If one does not stop to reflect on it (life) once in a while life will just pass them by like a shadow from the side of your eye that quickly disappears when you try to focus upon it. The very purpose of the painting may be to stop and reflect on the past; where you have been or accomplished in your life, and where you may see yourself in the years to come. The artist drew this painting to express his thoughts on what he was thinking at the time. The mirror is a symbolism object that the artist used to allow the viewer to relate and interpret his thoughts. The artist must have been aging at the time he drew the picture and his thoughts reflected his emotions. I believe he used a woman because women are emotional and symbolizes life. The women’s body produces life and before life can begin it has to develop. The baby develops in the womb and at the right time the baby is born and life starts. In time life changes from baby to toddler, adolescence, and adult, and one must take time to reflect on it before it is gone. In concluding the mirror represents reflection of what you see and what was and perhaps what will come; age. If you do not take time to reflect on yourself life will pass by just like a circle there is a beginning and an ending. The beginning of the circle is the start (birth) and as life develops the ending becomes closer to the beginning and once it touches life is complete. There will be no time left to reflect on life as it has passed by. The painting does not just represent females but males too. The painting is about life and reflecting on oneself before time runs out. There is a time for birth and a time to give birth but people in time will pass away. My first emotion when viewing the painting was time. One cannot buy time or stop time it keeps going despite of what is going on in it.

Saturday, September 28, 2019

Journal Essay Example | Topics and Well Written Essays - 250 words - 99

Journal - Essay Example All children believe in Santa Clause and love the magic of Christmas. So Coca Cola used it and built the association array, something like Santa Claus drinks Coca Cola and Christmas is not full without Coca Cola. At least I understood it in this way and asked to buy me a Cola. In this commercial one may also find the image of happy families, celebrating the holiday and enjoying positive emotions. Children like and need such things and these pictures capture childrens attention. Also the authors used the holiday song with very sticking to the memory tune. Eric Schlosser in his essay Kid Kustomers noticed â€Å"The growth in children’s advertising has been driven by efforts to increase not just current, but also future, consumption. Hoping that nostalgic childhood memories of a brand will lead to a lifetime of purchases (...)†. This pattern works in case of Christmas advertisement by Coca Cola. When I found the clip on YouTube I saw comments like â€Å"I dont feel Christmas until I see and hear that advert† (user pwnsauce8) or â€Å"i love coca cola adverts at christmas i always drink coke on christmas day† (user Ste OC). Also I remember the commercial of 7-UP with Orlando Jones. He plays with small dog and accidentally he hits the pet with the can of 7-UP. I was not cruel to animals, I liked dogs and liked to play with them. I imaged that the dog is kidding and pretending dead so it seemed very funny. This clip did not make me want 7-UP but it made me want a puppy. I asked my parents to buy me a dog every time I saw this video. Now I can say these clips contain no information about goods, its features, or price. There are only emotions and associative arrays in these videos. So the ideal audience of these advertisements has to be emotional and have no logical and critical thinking. Like kids. Basically these drinks are not for children as they contain a lot of harmful for childs body

Friday, September 27, 2019

Stress and coping Essay Example | Topics and Well Written Essays - 2750 words

Stress and coping - Essay Example Again sometimes certain happy occasions are considered â€Å"stressful†. For instance the birth of a child, moving to a new house, or promotion in the workplace may prove to be stressful. This may be because one is not prepared to deal with such events. Stress is personal and there are different forms and levels of stress. How one copes with stress varies from individual to individual. Each individual looks at a situation differently and hence copes with it differently. Often people react to situations with fear and anxiety, all signs of stress, because these situations had caused stress in the past. For instance a student who has failed in an examination may feel stressful the next time he takes an examination. Every individual exhibits different coping skills. Hence two persons will not respond to a situation in exactly the same way. If a person responds to stress in a negative way it may affect health and happiness. By understanding the stress inducing situation and responding accordingly one can handle stress effectively. Today in the modern world life is full of demands, worries and frustration, all causing a certain amount of stress. Stress has almost become a way of life. Stress per se is not bad. In small amounts it may motivate you and help you to perform better. But when a person is constantly under stress it may affect his mind and body. According to Hawkins (1994), â€Å"†¦too much or too little stress can have deleterious effects on performance with resultant effects on the health of the individual and the organization.† Again, the impact of stress on health depends on our perception of the event that causes stress and how we react to the situation. Sometimes an event may motivate or even energize us. For instance events such as taking a vacation or winning a game may energize you. Sometimes we may perceive an event as stressful and react to it in a way that can have a negative effect on our mental and physical health.

Thursday, September 26, 2019

Support the argument that warfare in the Napoleonic era is Essay

Support the argument that warfare in the Napoleonic era is fundamentally similar to warfare as it practicted today - Essay Example Today, we look back to the Napoleonic era and we find a direct link in the military reforms and tactics that were used during the 1792-1815 French revolution having a direct impact on our very own military structures and organizations (Brian 46). France revolution was the of a monarch regime breaking loose and transforming into a nation founded on equality for all. This evidently was not an easy process as it meant doing away with monarchial rule, the nobles and breaking free from the church. It also meant that people would seize from being referred to as subjects, and embrace citizens as a title (Stewart 29). This was a task that had the rest of Europe at odds with France. Late 1791, the French King sought the help of other Europe rulers to aid in his reinstatement. This officially resulted in the emergence of the French revolution in April 1792; with the French new nation aiming at bring change through battle throughout Europe. Their first victory was marked in Belgium at the end o f 1792 (Paul 25). The French armies were now composed of talented men from all parts and class of France as with a nation structure, citizens were all equals unlike subjects who were greatly divided by the class system. This was one of the strengths of the French military as with such a tactic, it had more soldiers at its disposal than others (Brian 45). Moreover with a common goal, and the zeal to overcome whatever form of obstacles, the French military had a bond that was previously scarcely heard of in Europe, the ‘trust’ bond. Soldiers from France were able to with ease exploit tactical maneuvers hence breaking logistical constrains a factor that proved to be advantageous in battle and a contributor to their numerous successes in the fields (Stewart 29). War had been declared and the first coalition was formed by seven nations namely: United Provinces, Great Britain, Spain, Austria, and Prussia. This was at the beginning of 1793, marking the beginning of the 23years of struggle by France against these Nations. This is what created the need of an exceptional military leader who could face up to this challenge (Paul 25).The leadership of the French army was dynamic and strategic, especially since March 1796 when the great Napoleon Bonaparte took over the position of general. Napoleon was a brilliant soldier, a genius of sorts. He was a leader who could gather troops of up to 300,000 or more troops and maneuver them to success against their enemies as was the case in 1812 in Russia. The treaty of Campo Formio is an evidence of the organized and brilliance of Napoleon as a French army leader as it resulted from the defeat of Sardinian and Austrian forces back in Italy that led to French domination of the Belgium and Luxembourg then known as Austrian Netherlands. These two regions were the first additions of the now growing French Republic (Stewart 30). The French made organizational changes to their army that increased there lethality and sparked military reform in other states. Under the governance of Napoleon, greatness was curved for France and other states. Napoleon went by

Wednesday, September 25, 2019

Why did Britain want a trading post on Singapore Research Paper

Why did Britain want a trading post on Singapore - Research Paper Example The Sultan of Singapore, Abdul Rahman, was under relatively tight Dutch control and as such, could not allow for the British to set up any trading post in Singapore. However Raffles formulated a plan through which the Sultan’s elder brother would be able to take up the sultanate. Sultan Abdul Rahman’s elder brother Tengku Hussein Shah was supposed to be the rightful ruler due to his having been the eldest son (Rahim, 2010). Sir Raffles drew up papers that effectively recognized Hussein Shah as being the lawful sultan of not only Johor, but also Singapore. After recognizing Hussein Shah as sultan, Sir Stamford Raffles signed a treaty in February 1819 with Hussein Shah and Temenggong Abdul Rahman, the treaty declared the approval the establishment of a British East India Company trading post in Singapore (Rahim, 2010). The treaty also specified that Sultan Hussein Shah and the Temenggong would in turn receive an annual income from the British. In the establishment of this trading post, it can be noted that Sir Raffles undertook a number of drastic measures in what can be construed to be an indicator of the importance that Britain attributed to the establishment of this trading post (Yew, 2013). This paper will seek to establish why Sir Stamford Raffles and Britain wanted a trading post in Singapore. The geographical location of Singapore is believed to have been one of the key reasons as to why the British essentially chose it as the location where they would set up a new port in the region. The Straits of Melaka had become an important trade route for British traders who would use it when travelling to China during the 19th century. The strait had proven to be a relatively great source of income for these British traders as a result of its facilitation of the lucrative opium-tea and silk trade with China (Yew, 2013). When using the route, British traders would travel from Europe, around the African continent to SEA,

Tuesday, September 24, 2019

Financial Management assignment Essay Example | Topics and Well Written Essays - 1500 words

Financial Management assignment - Essay Example There are also high chances that some portions of business and obviously some workforce could be laid off because Google of cost cutting measures. Many analysts believe that if Google can sell Motorola’s home division, either in part or as whole, then the revenues realised from the deal could easily infuse necessary cash into Motorola’s handset division and give a chance to turn around (Pcmag.com, 2012). The merger and acquisition was strategic from the point of view of Google as post merger Motorola will still be operating independently and that the deal will strengthen the existing patent portfolio of Google. Google was also suffering losses from numerous lawsuits related to patent infringements between its vendors and the likes of companies including Oracle Corporation, Apple Inc. and Microsoft. Hence, the deal is expected defend its expanded portfolio and viability of its Android operating system. Google Inc is mainly famous for its pioneering search technologies that it uses to connect billions of people around the world. The company was founded in the year 1998 by Larry Page and Sergey Brin, who holds PhD from Stanford. It is headquartered in Silicon Valley but its offices are spread across Europe, America and Asia. In the world of 21st century Google has earned the trophy of top web property in all major global markets. Google’s advertising segment are targeted to all types and size of businesses with quantifiable results. The company provides its users/customers enhancing web experience. Motorola Mobility is a multinational publicly traded telecommunications equipments corporation that is headquartered in Chicago, Illinois, United States. The company has huge contributions revolutionising the mobile phone industry through innovation and holds a cumulative track record of pioneering mobile handset business for over 80 years. At the time of merger and acquisition, Motorola Mobility was the owner of 17,000 patents, out of which

Monday, September 23, 2019

Ethical Argument Essay Example | Topics and Well Written Essays - 1250 words - 1

Ethical Argument - Essay Example Even so, Pope (530) warns against embracing such social change without understanding what is at stake. Despite the results of the opinion poll, only a handful of the American states allow the marriage between couples of the same sex with others reversing their earlier stand supporting the union. This could be an indication of the fact that this form of union goes against certain expected standard social norms. Therefore, same-sex marriage is socially deviant and should not be legalized. Civil marriage refers to a legal contract or social unions between two persons with the government, through its officials, performing, recording and recognizing it (Corvino and Gallagher 11). Marriage accords the couples exclusive rights and benefits. However, same-sex marriage brings forth a myriad of symbolic, religious and constitutional questions that has caused a continuous intense debate on the legalization of same-sex marriage (Pope 530). Gertsmann cites the Marriage Act 1961 which was amended in 2004 that defines marriage as the union between a man and woman and excludes all the others (15). This excludes same-sex marriage from being considered as marriage, a fact that has caused same-sex activists to push for change for their recognition in law. The case against same-sex marriage revolves around religious, moral and health concerns. By prohibiting homosexuality, a majority of religions, by extension, prohibit same-sex marriage. A majority of Christians argue that same-sex marriage is immoral and goes against the will of God and the reason of procreation that saw Him put man and woman together (Pope 533). In fact, Christians quote God talking of such a union as detestable in the Old Testament. Islam also prohibits same-sex marriage noting that the reason why Sodom was destroyed was because of such sins. Similarly, Hindus oppose same-sex marriage noting that for every soul, there exists another soul mate of the opposite sex. Since sex may

Sunday, September 22, 2019

Honor Essay Example | Topics and Well Written Essays - 500 words

Honor - Essay Example The Merriam Webster dictionary defines honour an ardent sense of what is described as ethical conduct. However, it is somewhat difficult to give the actual definition of honour in the modern times. The term may appear to have the same literal meaning in various languages however, various acts and behaviours are viewed as being honourable in the various cultures. This essay gives my own definition of the concept of honour and how its examples in the modern world. In my opinion honour is the ability of individuals to be themselves. Additionally, it refers to the ability of individuals to think independently and doing what they deem to be right. This is my definition of honour given the modern society is characterized by brainwashed people with justified opinions in all issues affecting society (Dailey 7). It takes an honourable individual with a real self-worth to think and act independently regardless of the trends in society or what other people think. In history, there have been honourable individuals that have set the example for the current and future generations. Honour has various meanings to different people. To some individuals, standing up for the rights of the minority is being honourable. Others may describe the missionaries serving in African countries as the best gesture on honour. While there believe that a soldier dying in war while fighting for their country as being honourable (Dailey 8). While these deeds are viewed as being honourable, they all revolve around the point that honour refers to the act of doing what is right. The individuals that advocated for the rights of the majority do it because it is right. The same applies for missionaries that go to African countries to preach the word of God. Finally, the soldiers that die in war do it to protect the rights and freedom of the citizens. While these incidences may vary, they have a major and common aspect, in all instances; these

Saturday, September 21, 2019

Stereotypical Roles Women Play In Advertisements Essay Example for Free

Stereotypical Roles Women Play In Advertisements Essay Since the commonly known creation Bible story of Adam and Eve, women have been viewed subsidiary to men; society has formed a bias that females cannot perform jobs equivalent to or of the same value as men. The model in Figure 1 is extremely feminine, for example: her nails are painted, she is wearing multiple rings on her fingers as she holds a light grip on the steering wheel, Since the commonly known creation Bible story of Adam and Eve, women have been viewed subsidiary to men; society has formed a bias that females cannot perform jobs equivalent to or of the same value as men. The model in Figure 1 is extremely feminine, for example: her nails are painted, she is wearing multiple rings on her fingers as she holds a light grip on the steering wheel, Advertisements help feed into the stereotypical image of women functioning as housewives and caretakers. One might ask: is advertising simply mirroring societies view on the roles of females, or are they part of the reason why America still labels women as domesticated? Printed advertisements portray women inferior to men by the use of their context, imagery, and content. Companies use the conventional view of women in marketing strategies in order to sell their products. Figure 1 â€Å"The Mini Automatic. For simple driving.† advertisement Source: Mini Automatic Transmission Printed Ad holds a light grip on the steering wheel, her hair is set in perfect curls, her make-up is flawless, and she appears to be dressed up for a special occasion. The expression on the women’s face displays her indecisiveness and insecurity of her driving abilities. Figure 1 states that the Mini Automatic is for â€Å"simple driving†, implying that the motorist is incapable of driving an automobile without difficulty. The advertisement is using the sentiment that women are inadequate drivers; it implies that if a woman is competent enough to maneuver the Mini Automatic, then it must be of simplicity. Before the 1950’s women in America were expected to cook, clean, and take care of the household, whereas men were looked at as the financial support system. Figures 2 and 3 are subliminally underlying the message of men doing a women’s role as a housewife. Both images contain the phrase â€Å"whipped so good†; meaning that if one buys Pinnacle Vodka, it will in turn reverse the classic expectation of women fulfilling household chores and encourage men to do so instead. The advertisements encourage the idea of men superiority because they are performing duties that are seen to be abnormal, such as doing laundry or ironing clothes. Before the 1950’s women in America were expected to cook, clean, and take care of the household, whereas men were looked at as the financial support system. Figures 2 and 3 are subliminally underlying the message of men doing a women’s role as a housewife. Both images contain the phrase â€Å"whipped so good†; meaning that if one buys Pinnacle Vodka, it will in turn reverse the classic expectation of women fulfilling household chores and encourage men to do so instead. The advertisements encourage the idea of men superiority because they are performing duties that are seen to be abnormal, such as doing laundry or ironing clothes. The main objective in Figure 4 Swiffer WetJet advertisement is for the audience to find a commonality between themselves and the mother standing in the kitchen. The advertisement displays a modern day housewife cleaning up after her child. The text states: â€Å"He made it in the kitchen and ate it in the dining room. With Swiffer WetJet, both floors were clean before he was.† Figure 5 shows two women in a clean kitchen with the Orbit logo â€Å"after any meal† indicating that their mothers who cook breakfast, lunch, and dinner for the family. Both Figure 4 and 5 exhibit women in the kitchen, either cleaning or cooking. Society struggles with gender expectations. In figures 1 through 5 women are suggestively thought of as ones who take care of the family and clean the house, whereas men generally take on the dominant role. Advertisements continue to use marketing strategies that are stereotypical to women because people still uphold the belief that men are superior. Advertisements are apart of the problem.

Friday, September 20, 2019

Gene Therapy In Genetic Engineering Applications

Gene Therapy In Genetic Engineering Applications Gene therapy is one of the applications of the genetic engineering. It is a technique which correcting defective gene that is responsible for disease development (cited Safdar, 2010). Gene therapy also involves the addition of healthy and functional copy of the faulty gene into the target cells of the body. Gene therapy generally works by inserting a normal gene into the genome to replace an abnormal gene in the target cells. There are two types of gene therapy. Firstly, germ line gene therapy which involves modification of genetic material in the gamete cells that would be heritable and can be pass through to the next generation. Secondly, somatic gene therapy which involves insertion of therapeutic gene into somatic cells of the patient that only effect to the individual patient only and will not be inherited by patients offspring.( cited in Ten Tailed Fox, 2009). Various genetic disorder diseases commonly are caused by faulty genes. With gene therapy, instead of treating the symptoms of the disease, treatment also target and correct the underlying cause of disease and eventually improve the faulty genes to normal genes. One of the genetic diseases that apply gene therapy as alternative treatment is Cystic Fibrosis. Cystic Fibrosis (CF) is one of the most well-known hereditary lethal diseases. A study conducted by UK Cystic fibrosis Gene Therapy Consortium (UK CFGTC) stated that approximately, 50 000 people and 1 in 2500 newborns around the world are affected. CF is an autosomal recessive disorder which caused by the mutation of Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) protein that leads to abnormally thick secretion of mucus. The organs most affected by CF are the lungs, gut, pancreases, liver and reproductive tract, but lung infection is the most serious affected by CF. (cited in Metharom, 1997). Continuous inflammation, damaged lungs and respiratory failure are results of repeated cycles of infection that may leads to death. With the development of effective treatment to overcome CF, gene therapy was introduced by scientist in 1990 which promises new opportunity for CF patients to have a better and long life span. This gene therapy involves replacing the detective CFTR gene with the normal one in the affected cells. As the results, the functional CFTR are being produced in all target cells and the CFTR gene will then conducts the production of normal CFTR protein which acts as a medium that allows releasing chloride and other ions. But this is opposite with people who have CF, where CFTR protein is detective and the cells do not discharge chloride ions. Although, gene therapy has the capability in treating CF, it still faces with various issues. This report consists of history of CF gene therapy and genetic techniques of gene therapy on CF. Research findings also include the advantages and disadvantages of using gene therapy in treating CF. 2.0 BACKGROUND GENETIC Gene therapy has shows that much positive feedback in treating genetic diseases although there are many failures happened. Gene therapy for CF first discovered in 1990 when scientist treated defective CFTR successfully and they added the normal copies of the gene to laboratory cell structures. The first experimental CF gene therapy treatment was given to CFs patient in 1993 (cited in Schoenstadt, 2009). The table below shows the major events that occurred due to development of gene therapy in treating Cystic Fibrosis. 3.0 GENETIC TECHNIQUES In gene therapies, there are three main techniques that are being used in treating diseases. The first is Gene addition, in which the genetic material is added to the target cells with no attempt to incorporate it into chromosomes. Second one is techniques of gene repair that replace abnormal segments of DNA in defective genes in their normal chromosomal site. The last one is Gene replacement techniques which allow deletion of the abnormal gene from its chromosome and replacement with a normal gene. (cited in Sade RM, Khushf G., 1998). In order to treat CF, the common technique used is Gene replacement by using vector. Vector is a DNA molecule (virus) act as a medium to transfer foreign genetic material into another cell. Instead of introducing new genetic material into target cells vectors are also agents to which new genetic material is attached. Diagram below shows the working of a virus acts a vector in gene therapy. First step to do is designing a vector by modifying the gene of the virus. We need to remove the rep gene which codes for proteins that responsible for viral replication as well as cap gene, which codes for capsid structural proteins. Then, we insert the normal CFTR gene in the virus. Second step is producing the virus. After inserting the CFTR gene in the virus, we transfer the vector into a packaging cell line so that the vector will combine with protein needed to assemble the virus. Next, we collect the virus sample from the growth medium and add into the Petri dish containing the CF cells. The virus give effect to the cell as it integrates the DNA into specific location on chromosome 19. Last step, we transfer the vector into CF patient. CFTR gene in the cell will transcribe into mRNA and this induces the cell to produce normal CFTR protein in the target cells. Diagram below show the mechanism of vector in treating Cystic Fibrosis. 4.0 SOCIAL ISSUES In recent years, many types of techniques have been developed to identify genes associated with specific diseases. Society always debate over the ethics of using gene technology to treat human beings when recombinant DNA research began. Tables below show advantages, disadvantages, ethical and social of practicing gene therapy to treat genetic diseases such as Cystic Fibrosis. ADVANTAGES OF GENE THERAPY Gene therapy promotes in providing better and normal life for those who practise the therapy. (Ten Tailed Fox, 2009). The practice of gene therapy on CF patients can solve their problems by replacing none functional gene with functional one. (cited in S. Muniba, 2010) Gene therapy has high success rate compared to other methods in treating CF disease. Gene therapy helps patients to avoid from practicing unnecessary treatment and alternative which may be dangerous to them. SOURCE: http://www.biotecharticles.com/Genetics-Article/Gene-Therapy-Advantages-and- Disadvantages-271.html DISADVANTAGES OF GENE THERAPY Scientist stated that correcting the defect in people who had diseases is much harder than achieving correction in cells in the laboratory .It means that there are also numbers of trial that results in failure. (cited in Healingwell.com ) Practice of gene therapy using vector may induce immune response in the patients. The gene that is injected or sprayed into patients target cells may trigger antibodies to kill the vectors. ( cited in William, 2000).This is because virus is used as a vector to transport the therapeutic gene. The use of gene therapy in treating CF will cause in diminishing the gene pool. Their patient s next generation will have to survive with the changes in their genomes.(cited in Sade RM, Khushf G., 1998 ). Chance of inducing a tumor .If the DNA is integrated in the wrong place in the genome, for example in a tumor suppressor gene, it could induce a tumor. (cited in Healingwell.com) SOURCE: http://academicdepartments.musc.edu/humanvalues/pdf/gene-therapy.pdf In conclusion, gene therapy is a best solution in treating cystic fibrosis because it has the high chances to eliminate this genetic disorder disease. Muniba stated that gene therapy could be last cure for every genetic disease. People who take gene therapy will make up their mind if they also face with this problem because this type of treatment can be the last hope for them in treating hereditary disease like Cystic Fibrosis.Government should concerns regarding the harms that may be associated with gene therapy and the beneficial uses of gene technology are required. (1547 words)